Innovation

Prevention is the best medicine

Prevention is about innovating to change the course of disease

Ahead Together in innovation

There’s never been a time when science and technology have formed such a powerful union as they do now. We’re able to identify drug discovery targets using genomics and AI/ML in a way that is unprecedented. We’re also able to use more approaches than ever before to design new medicines and vaccines to address the root cause of disease.

Tony Wood

Chief Scientific Officer

We get ahead of disease together by preventing and treating it with innovation in specialty medicines and vaccines. Our R&D approach combines our scientific focus on the immune system - with the use of advanced technologies.

We are working to deliver a new generation of differentiated, needed vaccines and medicines in four core therapeutic areas where we have the strongest expertise, and where significant patient need remains: respiratory, immunology and inflammation; oncology, HIV; and infectious diseases.

Technology powers all aspects of our R&D. We use human genetics and functional genomics, along with artificial intelligence and machine learning (AI/ML), to deeply understand the patient, human biology, and disease mechanisms. This is leading to real breakthroughs for tackling a range of conditions, such as liver disease, or transforming HIV treatment and prevention.

We believe the powerful combination of science and technology holds the key to fundamentally transforming medical discovery for the better, making the R&D process more dynamic, improving success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.

  • Medicines and vaccines in development in 2024

    71

  • Phase I programmes started in 2024

    9

Our pipeline

At GSK, our portfolio and pipeline is focused in developing medicines and vaccines in four core therapeutic areas, which are the areas of human health we focus on to prevent and treat disease: respiratory, immunology and inflammation; oncology; HIV and infectious diseases. We also consider opportunities in organic research and business development in other therapeutic areas, where there is a patient need and where the opportunity fits with our focus on human genetics, genomics, and the science of the immune system.

ASSETS
60+
potential vaccines and medicines
FOCUS
>70%
of these assets modulate the immune system
PHASE III
x2
the number of assets in phase III clinical development during the last 5 years

Our therapeutic areas

We prioritise research into new specialty medicines and vaccines, that can prevent and change the course of disease. We focus on four core therapeutic areas: respiratory, immunology and inflammation; oncology; HIV, and infectious diseases. These are areas where significant patient need remains and where we have the strongest expertise and greatest confidence in our ability to deliver differentiated and needed medicines and vaccines at scale.

We continue to strengthen our pipeline of medicines and vaccines, applying our growing expertise and partnerships in data and technology to increase the productivity of our R&D.

Respiratory, immunology and inflammation

Respiratory, immunology and inflammation

With our expertise in inflammation & immune system science, we target lung, liver & kidney diseases

Oncology

Oncology

Our ambition is to help increase quality of life, maximise survival and change the course of cancer

HIV

HIV

We work to end the global HIV epidemic with an industry-leading pipeline driven by patient insights

Infectious diseases

Infectious diseases

Our infectious diseases portfolio, and including HIV, is the broadest in the industry.

How we apply technology to get Ahead Together

We are at the forefront of health-related advances in science and technology, working to create innovative solutions to a range of healthcare challenges.

Advanced technology platforms such as AI, machine learning and functional genomics are central to our R&D approach. At the same time, diverse vaccine platform technologies including the use of adjuvants and mRNA technology have the potential to drive the next generation of vaccines and medicines. 

Global Technologies 

Clinical trials at GSK

Diseases and medicines can affect people differently depending on their race, ethnicity, sex or age. It’s therefore vital that we represent the real-world disease population in our clinical trials to advance our understanding of new vaccines and medicines, to create better health outcomes for the patients who rely on us.

Find out about our clinical trials process, how we work with doctors and volunteers throughout this process, and how to become a research volunteer.  

Clinical Trials 

Our Global R&D locations

Our leading R&D centres in the UK, US, Belgium and Italy are pivotal in helping us to get ahead of disease around the world.

Global R&D locations